Calcification & Inflammation


Calcification consists of calcium and phosphorous and is a normal process for building healthy bones and teeth. But it also plays a central role in disease conditions such as strokes and heart attacks.

Calcifying Nanoparticles (CNPs) form slow-growing calcified colonies in arteries and organs, much in the same way as coral reefs form.

CNP colony

Our company is devoted to discovering the link between calcification and Calcifying Nanoparticles.

Calcification of blood vessels typically involves the heart's coronary arteries in atherosclerosis. It occurs in arteries throughout the body in arteriosclerosis, or hardening of the arteries. Kidney stones are calcifications within the urinary tract.

Soft tissue calcifications are observed in other diseases such as, prostatitis (a painful inflammation of the prostate gland), and Polycystic Kidney Disease (growths of cysts in the kidneys).

CNPs have been found in many diseases associated with calcification.

The calcified material that they produce has been found to be responsible for inflammation that accompanies many diseases.

Inflammation is a normal response of the body to protect tissues from infection, injury or disease, but it can also harm the body when it becomes chronic.

The inflammatory response begins with production and release of chemical agents by cells in infected, injured or diseased tissue. These agents cause redness, swelling, pain, heat and loss of function.

Inflamed tissues generate additional signals that recruit leukocytes to the site of inflammation. Leukocytes destroy any infective or injurious agent, and remove cellular debris from damaged tissue.

The inflammatory response can be acute or chronic. Acute inflammation typically lasts only a few days.

This response usually promotes healing but, if uncontrolled, may become harmful.

The treatment of acute inflammation includes the administration of aspirin and other non-steroidal anti-inflammatory agents. It provides relief of pain and fever. But the treatment of chronic inflammation has been problematic for medical science.

Chronic Inflammation

Chronic inflammation becomes the problem rather than the solution to infection, injury or disease.

Chronically inflamed tissues continue to generate signals that attract leukocytes from the bloodstream. When leukocytes migrate from the bloodstream into the tissue they amplify the inflammatory response.

This chronic inflammatory response can break down healthy tissue in a misdirected attempt at repair and healing. Diseases characterized by chronic inflammation include, among others:

  • Atherosclerosis, including coronary artery disease;
  • Rheumatoid arthritis;
  • Prostatitis; and
  • Psoriasis.

 


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